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It's a normal and necessary part of tissue maintenance, but in hair follicles, excess apoptosis in the dermal papilla depletes the cell population that drives growth

Benefits: Longer duration of action compared to cyanocobalamin May require less frequent dosing Preferred for patients with certain medical conditions Population-Specific Formulation Preferences The choice between cyanocobalamin and hydroxocobalamin depends on individual patient needs

For 2 mg dose: 2 / 4 x 100 = 50 units Doses per vial at 2 mg daily: All multi-dose vials sit well within the 28-day reconstituted shelf life at the standard 2 mg daily dose

That is the reference document if you want the full picture