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Abstract The incretin hormone Glucagon-Like Peptide-1 (GLP-1) is best known for its incretin effect in restoring glucose homeostasis in diabetics, however, it is now apparent that it has a broader range of physiological effects in the body

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315 The results showed that, in the OA rat model, liraglutide could activate the PKA/CREB signaling pathway and inhibit the inflammatory response through this pathway, thereby alleviating OA symptoms

For patients in whom visceral fat accumulation is the primary concern particularly those with metabolic syndrome, fatty liver disease, or cardiovascular risk burden the evidence here is meaningfully stronger than for the other two peptides