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[DOI] [PMC free article] [PubMed] [Google Scholar] 255.Caradonna E., Nemni R., Bifone A., Gandolfo P., Costantino L., Giordano L., Mormone E., Macula A., Cuomo M., Difruscolo R., et al

reported that supplementation of IVM media with MV significantly increased the IVM rate and subsequent embryonic development

However, a 2025 systematic review analyzing five randomized controlled trials found no significant difference between spironolactone (used alone or with metformin) and metformin monotherapy in improving hirsutism scores, testosterone levels, or BMI over the short term

Its also not ideal for someone hoping for fast results without making small habit changes, since long-term progress still comes from steady, consistent routines