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The relatively stable size of the overall lesion can be explained by the fact that their slow rate of proliferation is offset by cell-attritional factors such as immunosurveillance

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Samples were then spun for 10 min in a microcentrifuge to pellet proteins, and supernatant was diluted 1:20 in buffer before being measured

This can also lead to stimulation of the sympathetic nervous system and downregulation of parasympathetic tone via the vagus nerve through the dorsal motor nucleus of the vagus