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32 Thereby, they stimulate insulin secretion and reduce glucagon secretion in a glucose-dependent manner, both effects contributing to the glucose-lowering activity (Figure 1)

That shape is what lets it bind to GLP-1 receptors and work the way it should

(10) By potentially lowering lipid peroxidation, Pal-GHK might indirectly help mitigate the alteration of DNA and proteins, potentially reducing risk factors that may otherwise lead to cellular damage

Particular attention is needed for insulin and sulfonylureas (hypoglycemia risk), oral contraceptives (reduced absorption), thyroid medications (altered absorption timing), and blood thinners (variable absorption)