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FDA-approved GLP-1 medications for weight management are indicated for adults with a BMI of 30 or greater, or a BMI of 27 or greater with at least one weight-related health condition

The polymerization of abnormal hemoglobin S upon deoxygenation in the tissues to form fibers in red cells causes the development of SCD, thus, generating deformations and blockages in the circulation

Pathological analysis of nasal mucosal tissue in mice showed that piperine-treated mice had reduced eosinophil migration and infiltration compared to the allergic rhinitis control group, further highlighting the therapeutic potential of piperine in allergic rhinitis (Aswar et al., 2015)

Head Neck (2019) 41:227784