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But with this progress comes responsibility ensuring that the delivery of these breakthrough therapies aligns with the sustainability imperatives of the future

Keating, J

Koska, J., Migrino, R

Thus, specific targeting of IGF-1R signaling post development may prove to be the best approach to achieve the benefits of low growth signals on healthspan and aging, without the potential unwanted side effects of combined adult-onset GH/IGF-1 deficiency