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Treatment continuation requires demonstration of adequate response: For liraglutide: at least 5% weight loss after 12 weeks at the maintenance dose of 3.0 mg For semaglutide: assessment after approximately 3 months at the maintenance dose of 2.4 mg, with discontinuation if less than 5% weight loss achieved Private prescribing is available but costs vary by provider and medication

They each contain a version of the thyroid hormones found in the body: thyroxine (T4), triiodothyronine (T3), or both

24-hour urine was collected, urine volume and collection duration were determined, and a sample analyzed for nitrogen and ketone bodies