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5 4) Tendon & connective-tissue pathways (GHR up-regulation) In tendon fibroblasts, BPC-157 up-regulates the growth-hormone receptor (GHR) at mRNA and protein levels and augments downstream JAK2 signaling in response to GHmechanisms consistent with tendon repair biology (in-vitro)

International Journal of Sport Nutrition and Exercise Metabolism, 25 (6), 607623

In insulin-resistant states, cellular glucose uptake is impaired even when insulin levels are elevated, forcing excess glucose into de novo lipogenesis pathways that create new fat rather than burning stored fat

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