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Proper form and progressive programming remain the priority

Phase 2 trial dosing used once-weekly subcutaneous injections with gradual escalation from 1 mg up to 12 mg to minimise gastrointestinal side effects

Osteoarthritis was no different, with the STEP 9 trial finding that Semaglutide improved patients' physical function and reduced their knee pain intensity (scores)

A gut-friendly diet typically includes: Fermented foods such as yogurt and kefir Prebiotic foods like garlic, onions, and bananas Polyphenol-rich foods including berries and green tea These foods help cultivate microbial diversity, which strengthens the gut-hormone signaling pathways involved in a natural GLP-1 boost (NIH)