2022, doi: 10.1001/jamainternmed.2022.3810
Thus, global increases of TCA cycle-related compounds reflect enhanced mitochondrial activity in liver, muscle, kidney, or other tissues 34 , since human RBCs lack mitochondria
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[3] The benefits of fiber We'll briefly gloss over the benefits of fiber, but for a more detailed read, the 2020 article recently published in Nutrients titled "The Health Benefits of Dietary Fibre" has a great modern overview, which cites not just standalone studies, but numerous meta-analyses also cited below: [4] Gut motility and constipation prevention [5] Body weight and abdominal body fat improvements [6,7] Insulin sensitivity and overall metabolic health improvements [8] Healthier gut microflora environment [9] Reduced inflammation [10,11] A minor improvement in mood [12] Lower rates of cardiovascular disease [13,14] Reduced risk of colorectal carcinoma [15,16] Lower overall mortality [17] Each of the studies cited above looks at various mechanisms, but most of them seem to be downstream of the fact that fiber helps the gut ferment short-chain fatty acids (SCFAs) , [18,19] which have incredible benefits ranging from anti-inflammatory activity [20] to a heart-protective reduction in TMAO (Trimethylamine-N-oxide)
