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OSMOTIC LAXATIVES Mechanism Draw water into bowel lumen Examples Lactulose Magnesium sulfate Magnesium hydroxide Polyethylene glycol Uses Acute constipation Hepatic encephalopathy (lactulose) Side Effects Diarrhea Electrolyte imbalance 4

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Users of triple agonists should be particularly vigilant about nutritional monitoring, as the more potent appetite suppression and metabolic effects may accelerate nutrient depletion