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Results: Significant reduction in modified MASI was observed in patients treated with topical and oral glutathione ( p =0.011) and ( p =0.007) respectively, while patients treated with topical or oral placebo had no response

It was so big that the dog had problems running

So, lets look at what the science says

ChaC1 is a proapoptotic enzyme under the regulation of CHOP (C/EBP homologue protein) transcription factor during the unfolding protein response of endoplasmic reticulum stress [24]