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Sunkar et al., 2003)

Consistently, the more pronounced transcriptional upregulation of profibrotic genes ( Col1a1, Fn1, Eln, Ccn2, Acta2, Col3a1 ) and kidney injury markers ( Ngal, Kim-1 ) was observed in Usp2 OE kidneys post-injury (Fig

For example, methionine (Met), found in meat, nuts, and legumes, can raise homocysteine (Hcy) levels if eaten in excess

It suggests that glutathione and other antioxidants, far from interfering with the activity of chemotherapy, appear to reduce side effects without decreasing efficacy and may, in fact, improve the efficacy of the chemotherapy in fighting cancer