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In comparison to Sermorelin, which binds directly to GHRH, Ipamorelin, another growth hormone-enhancing peptide and derivative of GHRP-1, improves overall growth rather than lean body mass enhancement

This highlights that while GHRP-2 has anabolic properties and can stimulate GH for lipolysis, its strong appetite-stimulating effect means that fat gain is possible if caloric intake is not carefully controlled

Cagrilintide is increasingly compared with established and investigational metabolic therapies as interest in obesity pharmacotherapy grows

Anticatabolic effects may occur by improving nitrogen balance either via increased protein synthesis or reduced protein degradation