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Why compounding pharmacies add vitamin B12 to tirzepatide formulations The addition of B12 to compounded tirzepatide addresses two primary concerns: nausea management and potential vitamin deficiency during treatment

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Verification with serum methylmalonic acid and/or serum homocysteine level may be necessary in asymptomatic patients with high-risk conditions, symptomatic patients with low-normal levels of vitamin B 12 (200 to 350 pg per mL), or symptomatic patients in whom vitamin B 12 deficiency is unlikely but must be excluded