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Circumstance: Starting GLP-1 medications Suggested interval: Baseline, then every 36 months Circumstance: Stable diabetes management Suggested interval: Every 6 months Circumstance: Poor diabetes control Suggested interval: Every 3 months Circumstance: General health screening Suggested interval: Annually Why early detection matters Regular monitoring enables early detection of medication side effects, treatment resistance, or developing complications before symptoms appear

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This matters as a new cornerstone therapy in type 2 diabetes (T2DM), glucagon-like peptide-1 receptor agonists (GLP-1), are entering broader use, necessitating a deeper dive into how this treatment interacts, directly or indirectly, with pathways influenced by sex hormones