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however, these findings do not translate directly to humans and are used only to guide preclinical experimental design

The goal is to provide fuel without triggering the nausea that many GLP-1 users experience when eating too much before exercise

Lidocaine and verapamil are both used to treat cardiac arrhythmias and have bioavailability less than 40%, but lidocaine is never given orally because its metabolites are believed to contribute to central nervous system toxicity

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