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corpus callosum in CAE), in the former, a deliberately orchestrated primary autoimmune process directed at myelin antigens results in lymphocytic infiltration, secondary injury to white matter and a universal innate response, whereas in CAE, where the primary insult is a biochemical one deliberately targeting intrinsic CNS myelin, following immune stimulation, the resulting lesion is pathologically similar (Day, 2005
KLOW is dosed similarly, with KPV added at the manufacturer-specified concentration
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Additionally, patients may be encouraged to adopt certain lifestyle modifications, such as avoiding heavy lifting or maintaining a healthy weight, to reduce the risk of aggravating the hernia
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