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Discovery and Optimization of a Series of Pyrimidine-Based Phosphodiesterase 10A (PDE10A) Inhibitors through Fragment Screening, Structure-Based Design, and Parallel Synthesis

Mice treated with antibiotics or reared germ free are resistant to KD-mediated seizure protection, whereas enrichment of Akkermansia muciniphila and Parabacteroides populations restores anti-epileptic effect of KD (76)

Daily injectable formats are rapidly contracting

For this reason, vegetarians and vegans benefit from being mindful of protein choices, as relying on a narrow range of plant proteins can make it harder to meet protein needs (2)