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The chemical structure was first described 20 years later, and it was in the 1970s that L-carnitine deficiencies were first discovered in humans [15]

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Colorectal Cancer Metastatic dMMR Immunotherapy (COMMIT) study: A randomized phase III study of atezolizumab (atezo) monotherapy versus mFOLFOX6/bevacizumab/atezo (FFX/bev) in the first-line treatment of patients (pts) with deficient DNA mismatch repair (dMMR) or microsatellite instability-high (MSI-H) metastatic colorectal cancer (mCRC) NRG-GI004/SWOG-S1610