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however, benchmarking studies reveal substantial heterogeneity among ORA tools in terms of biological informativeness and result specificity (de Oliveira et al., 2026)

Animals Thirty adult male Wistar rats, weighing between 180 and 220 grams and aged 8 to 9 weeks, were housed under standard conditions in the animal facility of the Faculty of Pharmacy at Kermanshah University of Medical Sciences

Antimicrobial peptide human -defensin-2 improves in vitro cellular viability and reduces pro-inflammatory effects induced by enteroinvasive Escherichia coli in Caco-2 cells by inhibiting invasion and virulence factors expression

doi: 10.1007/s00125-014-3231-y