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Int J Mol Sci (2019) 20(17):4092

Macrophages can secrete various cytokines, such as TNF-, IL-1, IL-6, IL-7, IL-15, IL-18, IL-23

Berberine patches are transdermal delivery systems designed to release berberinea naturally occurring alkaloid compound found in plants such as Berberis vulgaris (barberry)directly through the skin and into the bloodstream