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Oral semaglutide Nausea Abdominal pain Loss of appetite (can be more gradual) Diarrhea Injectable semaglutide Nausea Vomiting Constipation Potential injection site reactions Appetite suppression may feel stronger/faster Everyone reacts differentlyyour provider can help manage side effects during the adjustment period

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Aging relevance: B12 deficiency is dramatically underdiagnosed in adults over 60 proton pump inhibitor use, metformin use, and declining intrinsic factor production all impair B12 absorption