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Description

Hyperglycemia Associated With Pasireotide: Results From a Mechanistic Study in Healthy Volunteers

63 World Health Organization [WHO] (2018)

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The peptide's activation of ERK1/2 and downstream transcription factors including Egr-1 drives expression of collagen synthesis genes while its enhancement of cellular migration ensures efficient fibroblast recruitment to sites requiring matrix deposition, creating optimal conditions for rapid yet organized tissue reconstruction