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[263] Few years later, Zander et al., in a non-randomized parallel group study, showed that six weeks of continuous subcutaneous infusion of GLP-1 not only reduced fasting and postprandial plasma glucose concentrations, but also lowered glycosylated hemoglobin (A1C) by 1.3%, and induced up to a 2 kg reduction in body weight

Retatrutide is a relatively large molecule, and aggressive reconstitution can denature portions of it, reducing potency