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The article frames that as a decision point where a provider weighs escalation, switching medication, combination therapy, or investigating barriers such as poor adherence, diet quality or unaddressed metabolic conditions

To help normalize this experience, review the data below highlighting estimated symptom prevalence during the initial titration phase, alongside their specific physiological triggers: The most reassuring takeaway from large-scale clinical trials is that these symptoms are transient

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Int Arch Allergy Immunol, 99: 204-207