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(B6, especially in the pyridoxine form, is one of the few B vitamins that can lead to toxicity when used in excess.) Threonine is also important to gut barrier integrity in the small intestine, and I have read some reports of it helping with minimizing reactions to gluten, although I have not studied this in great depth yet

[DOI] [PubMed] [Google Scholar] 9.Sawyer TK, Sanfilippo PJ, Hruby VJ, et al

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GLP-1 medications bind to and activate the GLP-1 receptor in the brain, pancreas, gut, heart, liver, kidneys and blood vessels, triggering a wide range of beneficial metabolic effects. Meanwhile, tirzepatide is a dual GIP/GLP-1 receptor agonist that targets both GIP and GLP-1 receptors