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Hedgehog signaling and BMP4 facilitates the proliferation of fetal HPCs in vitro (Wang et al., 2015), while TGF signaling remarkably inhibits HPC colony formation in vitiro ( Our lab established a protocol consisting of EGF, CHIR, E616452 and two bioactive lipids lysophosphatidic acid and sphingosine 1-phosphate, hereafter termed as ECELS
Ann Thorac Surg 94(3):914-20, 2012
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