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Description

Glucose deprivation activates AMPK/FoxO3a by binding to FoxO3a and inhibiting SLC7A11 expression, thus preventing erastin-induced ferroptosis

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pubmed.ncbi.nlm.nih.gov/24791752/ Weschawalit S et al

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Laboratory studies using 5-amino-1MQ in aged animal models have revealed that NNMT inhibition modulates many age-associated metabolic parameters, including alterations in muscle tissue metabolism and cellular stress response pathways

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