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Overall, clinical trials consistently demonstrate a dose-dependent effect, with higher maintenance doses producing greater average weight loss

The Bottom Line GLP-1 receptor agonist medications are changing lives for many people, but they also change the way the digestive system works and, for many users, reduce the dietary fiber and nutrient diversity that a healthy gut microbiome depends on

Quick tip: If your question is about trial participation, start with the sponsor or ClinicalTrials.gov rather than product ordering information

As millions of people have been taking these weight loss drugs (Ozempic,Wegovy/semaglutide and Victoza, Saxenda/liraglutide), researchers are now documenting increased problems for bone strength and uric acid metabolism