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Both trials will assess once-weekly VK2735 over 78 weeks, with participants being randomly assigned to 7.5 mg, 12.5 mg or 17.5 mg of the study drug or placebo

On the molecular level, updated studies show that A and Tau pathologies cause progressive axonal degeneration and drastic downstream impairments in the synaptic processes (Pereira et al., 2021)