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The average time from symptom onset to definitive diagnosis ranges from 7 to 12 years across different healthcare systems, a delay that would be considered unacceptable for most other chronic conditions (Surrey et al., 2020)

The practical rule: Refrigerate at 2 to 8 degrees C, minimize air exposure by keeping caps tightly sealed, and avoid products stored or shipped at room temperature for extended periods

HA injections reported that PRP patients had better pain relief and functional improvement at 6 and 12 months post-treatment , whereas HA benefits diminished after 6 months (PMID: 30212925)

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