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Recombinant protein production can be carried out in a variety of platforms, each coming with its own advantages and disadvantages regarding yields, regulatory compliance, cost, scalability, flexibility, speed and safety (Table 2) 81,82

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Topiramate is highly teratogenic and requires strict adherence to pregnancy prevention measures Red flag symptoms requiring urgent medical attention include: Severe, persistent abdominal pain (which could indicate pancreatitis) Right upper quadrant pain, fever, or jaundice (possible gallbladder problems) Signs of dehydration (dizziness, reduced urination, extreme thirst) Chest pain, palpitations, or significant breathlessness Severe mood changes, depression, or suicidal thoughts Visual disturbances or severe headaches Allergic reactions (rash, swelling, difficulty breathing) Your doctor can provide personalised advice based on your medical history, current medications, weight loss goals, and individual risk factors

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