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No participants withdrew from any trial due to tolerability issues, indicating that even when side effects occurred, they were sufficiently manageable that participants chose to continue treatment

First, much of this consensus about Methionine is based on a few small studies

Eating healthy and exercising are important, not just for NAD+ production, but for overall better health and supporting every system that relies on cellular energy

B12 deficiency can also be an issue if you have had weight loss surgery, have a very poor diet, or follow extreme or restrictive diets for a long time