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Other common side effects include: Decreased appetite, which is partly the point but can become excessive Fatigue, especially in the first few weeks Injection site reactions like redness or mild swelling Belching and bloating Heartburn and acid reflux These are not rare edge cases

It slows gastric emptying, enhances satiety, and reduces brain reward signals for food

Spillantini M

The effect of nanomicelle curcumin supplementation and Nigella sativa oil on the expression level of miRNA-21, miRNA-422a, and miRNA-503 gene in postmenopausal women with low bone mass density: A randomized, triple-blind, placebo-controlled clinical trial with factorial design