59 Kastin and Akerstrom established in a landmark study that peripherally injected Exendin-4 passed readily through the BBB, facilitated by its lipophilicity, rather than becoming trapped in the endothelial cell
Serum IgE detection To test total IgE levels, mouse sera samples were diluted 10-fold and measured using IgE Mouse Uncoated ELISA Kit (#88-50460-88, Thermo Fisher, USA) according to the manufacturers instructions
J Bone Miner Res 35(8):14151423 Herrou J, Mabilleau G, Lecerf JM, Thomas T, Biver E, Paccou J (2024) Narrative review of effects of Glucagon-Like Peptide-1 Receptor Agonists on bone health in people living with obesity
Studies have shown improvements in the cardiac function of cocker spaniels and boxers with dilated cardiomyopathy, though the results are not as consistent for other breeds with the same condition