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Rotating Injection Sites to Reduce Skin Reactions Rotating injection sites moving at least 12 cm from the previous spot and alternating between body regions prevents lipohypertrophy and ensures consistent drug absorption

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These findings are consistent with preclinical results in which chronic lithium treatment alleviates oxidative stress induced by chronic variable stressors (e.g., restraint and noise) in rats showing depression-like symptoms via increasing SOD and total antioxidant activity [94]