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The growing rate of antibiotic resistance has also become a challenge (Yildiz et al., 2021)

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Since the bovine liver is limited to oxidizing NEFA, triacylglycerol (TAG) accumulation may frequently occur (Trevisi et al., 2012)

Current approaches are largely restricted to experimental settings, while available inhibitors, such as non-specific antioxidants or iron chelators, exhibit limited specificity and raise safety concerns related to off-target effects and disruption of systemic iron homeostasis