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P-01 Hereditary angioedema with normal C1-INH and PLG muta-tion treated with tranexamic acid: Beware of the risk of thrombosis Alexis Bocquet, David Launay, Isabelle Boccon-Gibod, Aurlie Du-Thanh, Delphiine Gobert, Sbastien Sanges, Laurence Bouillet Launay &Sanges University of Lille, U1286-INFINITE-Institute for Translational Research in Inflammation, F-59000, INSERM, and the Department of Internal Medicine and Clinical Immunology, CHU Lille, National Reference Center for Angioedema (CREAK), Lille, France Allergy, Asthma & Clinical Immunology 2025, 21(Suppl 2) :P-01 Introduction: The anti-fibrinolytic, tranexamic acid (TA) can be proposed as a long term prophylaxis for hereditary angioedema (HAE), and seems to be specifically efficient for HAE with plasminogen gene mutation (HAE-PLG), a subset of HAE with normal C1-INH (HAE-nC1-INH)

Oral supplements are suitable for general maintenance or mild deficiencies, while topical applications can deliver magnesium through the skin to relieve muscle tension or soreness

She incorporates activities that support muscle tone and bone health, ensuring she remains strong and independent for years to come

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