Those impurities might include truncated peptide sequences, deletion variants missing one or more amino acids, oxidized forms of the peptide, or residual solvents from the synthesis process
Fortunately, in May 2019, another GLP-1 drug, polyethylene glycol loxenatide, was launched, effectively alleviating this embarrassing situation
Introduction Alzheimers disease (AD), a global public health priority, is the most common neurodegenerative disease ( Some human and animal studies show that insulin can accelerate the clearance level of A in the brain and affects the phosphorylation of tau protein, meanwhile, enhances the synaptic activity and plasticity of neurons ( Glucagon-like peptides 1 (GLP-1), derived from intestinal L cells, is an incretin hormone
They also had no use of the medications of interest within the past year