This can result in a sunken facial appearance and further fitting issues
Most common causes of the discolouration include: Medications amino-salicyclic acid derivatives mesalazine/paraaminosalycylic acid/sulfasalazine doxorubicin , hydroxocobalamin , ibuprofen, phenothiazines, phenolphthalein, propofol , rifampicin/rifampin Dietary ingestants beeturia , rhubarb, blackberries, food dyes Metabolic abnormalities porphyria , urate crystals Hydroxocobalamin Early features of cyanide poisoning include nausea, vomiting, headache, dyspnoea, tachypnoea, hypertension, tachycardia, collapse and seizures
Why this trial matters: First bispecific + CD38 combo to show superior PFS and OS in Phase III in RRMM Potential new standard of care as early as second-line Demonstrates deep responses, high MRD-negativity, and durable outcomes First-line Strategies in BRAF V600E-Mutant mCRC: Real-World Evidence Signals Treatment Priorities In a real-world retrospective cohort of patients with BRAF V600E-mutant metastatic colorectal cancer (mCRC), frontline chemotherapy plus anti-VEGF therapy was associated with the longest survival outcomes, while BRAF-targeted strategies showed promising response rates, emphasizing the need for tailored therapy and prospective validation
If you are working in a biosafety cabinet, ensure airflow is running
