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Research on direct weight-loss impact is limited, formulas vary, and resultsif anyare usually tied to the overall plan rather than the shot alone

doi: 10.3389/fbioe.2025.1729166 Received 21 October 2025 Revised 01 December 2025 Accepted 17 December 2025 Published 15 January 2026 Volume 13 - 2025 Edited by Ling Wang, Dalian Medical University, China Reviewed by Nicola Alessio, University of Campania Luigi Vanvitelli, Italy Yesuf Adem Siraj, Bahir Dar University, Ethiopia Updates Copyright 2026 Hu, Li, Hu, Shan, Tang, Jiang, Yi, Chen, Jin, Wang and Wang

While Semaglutide works by mimicking a single hormone, GLP-1, to regulate appetite and blood sugar, Tirzepatide is a dual agonist that targets both GLP-1 and a second hormone, GIP

Scutellaria baicalensis extracts restrict intestinal epithelial cell ferroptosis by regulating lipid peroxidation and GPX4/ACSL4 in Colitis