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Melanotan I and II mimic the action of an endogenously occurring hormone, which plays a role in skin color

These GLP-1 receptor agonists work by mimicking natural hormones that regulate appetite, slowing gastric emptying, and improving insulin sensitivity

Anecdotal reports from research subjects and biohacking communities describe body composition improvements, increased subjective energy and mental clarity, and minimal side effects, though these uncontrolled observations require cautious interpretation and cannot substitute for rigorous clinical trials

Clinical trial data shows average weight loss of 10-15% of body weight over six months at therapeutic doses, with results continuing through month three and beyond