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Glucagon-like peptide-1 (GLP-1) analogs alter the activity of hypothalamic neurons in the arcuate nucleus, which are directly associated with eating behavior, thereby increasing satiety and reducing energy intake, leading to weight loss [11, 12]

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Melanotan-II interacts with several melanocortin receptors, including MC3R and MC4R, which influence appetite and sexual function

* Correspondence: Serge Chooklin, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers