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Divulgacin cientfica

MuSC Proliferation In aged skeletal muscle, NNMT overexpression is linked to impaired NAD+ salvage, dysregulated SIRT1 activity, and increased muscle stem cell (MuSC) senescence

Animals and cachexia model The mouse colon cancer cell line, CT26, which shows high tumorigenicity and low metastatic potential [29], was implanted into mice to generate an in vivo cancer cachexia model [8, 29, 30]