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As illustrated by the GLP-1 experience, such limitations can delay translation by decades without invalidating the underlying biology ( Underexploration, as defined here, therefore reflects historical and technological context rather than intrinsic therapeutic inadequacy

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However, the authors of this study noted that there were no clinically significant differences, and both drugs were effective for their intended uses

The lower list price is intended to connect more people with our innovative medicines, specifically those whose out-of-pocket costs are linked to list price, such as individuals with high-deductible health plans or co-insurance benefit designs. The announcement notes that the price decrease will only impact the list price