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doi: 10.1111/j.1365-4632.2010.04381.x 61 KimCCBerryEGMarchettiMASwetterSMLimGGrossmanDet al
10.1016/j.exger.2007.05.004 91 LiX.ChauhanA.SheikhA
Its worth noting that retatrutides safety profile appears broadly consistent with other peptide-based treatments like semaglutide and tirzepatide, which also carry gastrointestinal considerations
The peptide reduces production of pro-inflammatory cytokines including IL-1, TNF-, and IL-6 while enhancing expression of anti-inflammatory mediators such as IL-10 and TGF-, creating a cytokine milieu that supports tissue repair rather than ongoing damage
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