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Additionally, for the organic acidemias, methylmalonic and propionic acidemia (OMIM 251000 and 606054, respectively), monthly prophylactic treatment with the antibiotic metronidazole is also commonly used to reduce intestinal bacteria and the affiliated production of propionate, and this may confer the unexpected benefit of reducing TMAO production as well (Thompson et al

Knockdown of GCH1 significantly activated ferritin autophagy upon erastin treatment, which was reversed by using an autophagy inhibitor

Lipid hydroperoxides accumulate in the cellular membranes of lung cells, destabilizing the barrier functions of alveolar epithelial and endothelial cells