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In this depiction, each Cd(II) ion is tetra-coordinated by four cysteine ligands: two are deprotonated to yield (formally) Cd-thiolate conjugates that are similar in principle to those of glutathione and of other soluble thiols, while other two complete the coordination sphere

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Atherosclerosis 105:165170 Junaid MA, Kowal D, Barua M, Pullarkat PS, Sklower Brooks S, Pullarkat RK (2004) Proteomic studies identified a single nucleotide polymorphism in glyoxalase I as autism susceptibility factor